A Stromal Cell-Derived Factor 1α Analogue Improves Endothelial Cell Function in Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome

Abstract Endothelial cell (EC) dysfunction is a critical mediator of the acute respiratory distress syndrome (ARDS). Recent studies have demonstrated that stromal cell-derived factor 1α (SDF-1α) promotes EC barrier integrity. Our previous studies used a SDF-1α analogue CTCE-0214 (CTCE) in experiment...

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Bibliographic Details
Main Authors: Changrun Guo, Andrew Goodwin, Joy N Jones Buie, James Cook, Perry Halushka, Kelley Argraves, Basilia Zingarelli, Xian Zhang, Liping Wang, Hongkuan Fan
Format: Article
Language:English
Published: BMC 2016-03-01
Series:Molecular Medicine
Online Access:http://link.springer.com/article/10.2119/molmed.2015.00240