Lamin A, Chromatin and FPLD2: Not Just a Peripheral Ménage-à-Trois

At the nuclear periphery, the genome is anchored to A- and B-type nuclear lamins in the form of heterochromatic lamina-associated domains. A-type lamins also associate with chromatin in the nuclear interior, away from the peripheral nuclear lamina. This nucleoplasmic lamin A environment tends to be...

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Bibliographic Details
Main Authors: Nolwenn Briand, Inswasti Cahyani, Julia Madsen-Østerbye, Jonas Paulsen, Torunn Rønningen, Anita L. Sørensen, Philippe Collas
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2018.00073/full