Transcriptional changes associated with breast cancer occur as normal human mammary epithelial cells overcome senescence barriers and become immortalized

Transcriptional changes associated with breast cancer occur as normal human mammary epithelial cells overcome senescence barriers and become immortalized

<p>Abstract</p> <p>Background</p> <p>Human mammary epithelial cells (HMEC) overcome two well-characterized genetic and epigenetic barriers as they progress from primary cells to fully immortalized cell lines <it>in vitro</it>. Finite lifespan HMEC overcome a...

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Bibliographic Details
Main Authors: Jelinsky Scott A, Whitley Maryann Z, Garbe James C, Saraf Katie, Tunkey Chris, Lee Jee, Li Jian-Liang, Pan Jing, Li Yizheng, Stampfer Martha R, Haney Steven A
Format: Article
Language:English
Published: BMC 2007-01-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/6/1/7

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http://www.molecular-cancer.com/content/6/1/7

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