Two open states of P2X receptor channels

The occupancy of the ATP binding sites of P2X receptor (P2XR) channels causes the rapid opening of a small cation-permeable pore, followed by a gradual dilation that renders the pore permeable to large organic cations. Electrophysiologically, this phenomenon was shown using whole-cell current record...

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Bibliographic Details
Main Authors: Milos B. Rokic, Stanko S. Stojilkovic
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-11-01
Series:Frontiers in Cellular Neuroscience
Subjects:
ATP
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00215/full