The Placental Gene PEG10 Promotes Progression of Neuroendocrine Prostate Cancer

The Placental Gene PEG10 Promotes Progression of Neuroendocrine Prostate Cancer

More potent targeting of the androgen receptor (AR) in advanced prostate cancer is driving an increased incidence of neuroendocrine prostate cancer (NEPC), an aggressive and treatment-resistant AR-negative variant. Its molecular pathogenesis remains poorly understood but appears to require TP53 and...

Full description

Bibliographic Details
Main Authors: Shusuke Akamatsu, Alexander W. Wyatt, Dong Lin, Summer Lysakowski, Fan Zhang, Soojin Kim, Charan Tse, Kendric Wang, Fan Mo, Anne Haegert, Sonal Brahmbhatt, Robert Bell, Hans Adomat, Yoshihisa Kawai, Hui Xue, Xin Dong, Ladan Fazli, Harrison Tsai, Tamara L. Lotan, Myriam Kossai, Juan Miguel Mosquera, Mark A. Rubin, Himisha Beltran, Amina Zoubeidi, Yuzhuo Wang, Martin E. Gleave, Colin C. Collins
Format: Article
Language:English
Published: Elsevier 2015-08-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715007524

Internet

http://www.sciencedirect.com/science/article/pii/S2211124715007524

Similar Items