Pathophysiological defects and transcriptional profiling in the RBM20-/- rat model.

Our recent study indicated that RNA binding motif 20 (Rbm20) alters splicing of titin and other genes. The current goals were to understand how the Rbm20(-/-) rat is related to physiological, structural, and molecular changes leading to heart failure. We quantitatively and qualitatively compared the...

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Bibliographic Details
Main Authors: Wei Guo, Jonathan M Pleitner, Kurt W Saupe, Marion L Greaser
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3868568?pdf=render