Pulmonary Procoagulant and Innate Immune Responses in Critically Ill COVID-19 Patients

Pulmonary Procoagulant and Innate Immune Responses in Critically Ill COVID-19 Patients

RationaleSystemic activation of procoagulant and inflammatory mechanisms has been implicated in the pathogenesis of COVID-19. Knowledge of activation of these host response pathways in the lung compartment of COVID-19 patients is limited.ObjectivesTo evaluate local and systemic activation of coagula...

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Bibliographic Details
Main Authors: Esther J. Nossent, Alex R. Schuurman, Tom D.Y. Reijnders, Anno Saris, Ilse Jongerius, Siebe G. Blok, Heder de Vries, JanWillem Duitman, Anton Vonk Noordegraaf, Lilian J. Meijboom, René Lutter, Leo Heunks, Harm Jan Bogaard, Tom van der Poll
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
COVID-19
persistent ARDS
coagulation
innate immune response
bronchoalveolar space
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.664209/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.664209/full

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