Matrix feedback enables diverse higher-order patterning of the extracellular matrix.

The higher-order patterning of extra-cellular matrix in normal and pathological tissues has profound consequences on tissue function. Whilst studies have documented both how fibroblasts create and maintain individual matrix fibers and how cell migration is altered by the fibers they interact with, a...

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Bibliographic Details
Main Authors: Esther Wershof, Danielle Park, Robert P Jenkins, David J Barry, Erik Sahai, Paul A Bates
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-10-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1007251