Transcriptomic analysis of brain tissues identifies a role for CCAAT enhancer binding protein β in HIV-associated neurocognitive disorder

Transcriptomic analysis of brain tissues identifies a role for CCAAT enhancer binding protein β in HIV-associated neurocognitive disorder

Abstract Background HIV-associated neurocognitive disorders (HAND) persist in the era of combined antiretroviral therapy (ART) despite reductions in viral load (VL) and overall disease severity. The mechanisms underlying HAND in the ART era are not well understood but are likely multifactorial, invo...

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Bibliographic Details
Main Authors: Saranya Canchi, Mary K. Swinton, Robert A. Rissman, Jerel Adam Fields
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Journal of Neuroinflammation
Subjects:
HIV
Brain
C/EBPβ
Neuron
Astroglia
Neuroinflammation
Online Access:http://link.springer.com/article/10.1186/s12974-020-01781-w

Internet

http://link.springer.com/article/10.1186/s12974-020-01781-w

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