Dysregulation of HGF/c-Met Signal Pathway and Their Targeting Drugs in Lung Cancer

C-MET is a coding product of proto oncogene c-MET, hepatocyte growth factor (HGF) receptor with tyrosine kinase activity. The abnormal expression of c-Met gene is correlated with the tumorigenesis and development of lung cancer. Once the tyrosine kinase is activated by the interaction between the HG...

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Bibliographic Details
Main Authors: Yongwen LI, Hongyu LIU, Jun CHEN
Format: Article
Language:zho
Published: Chinese Anti-Cancer Association; Chinese Antituberculosis Association 2014-08-01
Series:Chinese Journal of Lung Cancer
Subjects:
HGF
Online Access:http://dx.doi.org/10.3779/j.issn.1009-3419.2014.08.08