EZH2 as a therapeutic target for multiple myeloma and other haematological malignancies

Abstract Enhancer of zeste homolog 2 (EZH2) is a histone methyltransferase that is of great interest in human cancer. It has been shown to have a dual nature, as it can act as a gene repressor or activator. Studies have highlighted the various roles of EZH2 in the pathophysiology of multiple myeloma...

Full description

Bibliographic Details
Main Authors: Rosemarie Tremblay-LeMay, Nasrin Rastgoo, Maryam Pourabdollah, Hong Chang
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Biomarker Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40364-018-0148-5