Subtype-specific differentiation of cardiac pacemaker cell clusters from human induced pluripotent stem cells

Subtype-specific differentiation of cardiac pacemaker cell clusters from human induced pluripotent stem cells

Abstract Background Human induced pluripotent stem cells (hiPSC) harbor the potential to differentiate into diverse cardiac cell types. Previous experimental efforts were primarily directed at the generation of hiPSC-derived cells with ventricular cardiomyocyte characteristics. Aiming at a straightf...

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Bibliographic Details
Main Authors: Patrick A. Schweizer, Fabrice F. Darche, Nina D. Ullrich, Pascal Geschwill, Boris Greber, Rasmus Rivinius, Claudia Seyler, Karin Müller-Decker, Andreas Draguhn, Jochen Utikal, Michael Koenen, Hugo A. Katus, Dierk Thomas
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Stem Cell Research & Therapy
Subjects:
Pacemaker
Pluripotent stem cells
Automaticity
Differentiation
Online Access:http://link.springer.com/article/10.1186/s13287-017-0681-4

Internet

http://link.springer.com/article/10.1186/s13287-017-0681-4

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