Modelling Nonalcoholic Steatohepatitis In Vivo—A Close Transcriptomic Similarity Supports the Guinea Pig Disease Model

Modelling Nonalcoholic Steatohepatitis In Vivo—A Close Transcriptomic Similarity Supports the Guinea Pig Disease Model

The successful development of effective treatments against nonalcoholic steatohepatitis (NASH) is significantly set back by the limited availability of predictive preclinical models, thereby delaying and reducing patient recovery. Uniquely, the guinea pig NASH model develops hepatic histopathology a...

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Bibliographic Details
Main Authors: Josephine Skat-Rørdam, David H. Ipsen, Stefan E. Seemann, Markus Latta, Jens Lykkesfeldt, Pernille Tveden-Nyborg
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Biomedicines
Subjects:
nonalcoholic steatohepatitis
fibrosis
transcriptome
animal model
guinea pig
biomarkers
Online Access:https://www.mdpi.com/2227-9059/9/9/1198

Internet

https://www.mdpi.com/2227-9059/9/9/1198

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