DOG1 is commonly expressed in pancreatic adenocarcinoma but unrelated to cancer aggressiveness

DOG1 is commonly expressed in pancreatic adenocarcinoma but unrelated to cancer aggressiveness

Background DOG1 (ANO1; TMEM16A) is a voltage-gated calcium-activated chloride and bicarbonate channel. DOG1 is physiologically expressed in Cajal cells, where it plays an important role in regulating intestinal motility and its expression is a diagnostic hallmark of gastrointestinal stromal tumors (...

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Main Authors: Kristina Jansen, Franziska Büscheck, Katharina Moeller, Martina Kluth, Claudia Hube-Magg, Niclas Christian Blessin, Daniel Perez, Jakob Izbicki, Michael Neipp, Hamid Mofid, Thies Daniels, Ulf Nahrstedt, Christoph Fraune, Frank Jacobsen, Christian Bernreuther, Patrick Lebok, Guido Sauter, Ria Uhlig, Waldemar Wilczak, Ronald Simon, Stefan Steurer, Eike Burandt, Andreas Marx, Till Krech, Till Clauditz
Format: Article
Language:English
Published: PeerJ Inc. 2021-08-01
Series:PeerJ
Subjects:
DOG1
Immunohistochemistry
Pancreatic adenocarcinoma
Tissue micro array
Online Access:https://peerj.com/articles/11905.pdf

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https://peerj.com/articles/11905.pdf

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