Stage specific requirement of platelet-derived growth factor receptor-α in embryonic development.

Stage specific requirement of platelet-derived growth factor receptor-α in embryonic development.

Platelet-derived growth factor receptor alpha (PDGFRα) is a cell-surface receptor tyrosine kinase for platelet-derived growth factors. Correct timing and level of Pdgfra expression is crucial for embryo development, and deletion of Pdgfra caused developmental defects of multiple endoderm and mesoder...

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Bibliographic Details
Main Authors: Chen Qian, Carol Wing Yan Wong, Zhongluan Wu, Qiuming He, Huimin Xia, Paul Kwong Hang Tam, Kenneth Kak Yuen Wong, Vincent Chi Hang Lui
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5608218?pdf=render

Internet

http://europepmc.org/articles/PMC5608218?pdf=render

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