Oral administration of MnCl2 attenuated hyperlipidemia-related cardiac remodeling in ApoE−/− mice

Oral administration of MnCl2 attenuated hyperlipidemia-related cardiac remodeling in ApoE−/− mice

Manganese chloride (MnCl2) has been shown to inhibit the Yes-associated protein (YAP) in high-fat diet-fed ApoE−/− mice. Although YAP has been implicated in atherogenesis, there are limited data on the effects of MnCl2 on cardiac remodeling. In this study, we discovered, by electrocardiography, that...

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Bibliographic Details
Main Authors: Han-Xiao Zhang, Cheng-Shun Zhang, Rui-Zhen Huang, Xin Cao, Xiao-Qin Dai, Chuan-Yi Zuo, Peng Lv, Li-Juan Zhu, Shu-Guang Yu
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:Journal of Pharmacological Sciences
Subjects:
Hyperlipidemia
Supraventricular arrhythmia
Cardiac remodeling
MnCl2
Atherosclerosis
Online Access:http://www.sciencedirect.com/science/article/pii/S134786132030116X

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http://www.sciencedirect.com/science/article/pii/S134786132030116X

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