Impact of Preanalytical and Analytical Methods on Cell-Free DNA Diagnostics

While tissue biopsy has for the longest time been the gold-standard in biomedicine, precision/personalized medicine is making the shift toward liquid biopsies. Cell-free DNA (cfDNA) based genetic and epigenetic biomarkers reflect the molecular status of its tissue-of-origin allowing for early and no...

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Bibliographic Details
Main Authors: Jure Krasic, Irena Abramovic, Alen Vrtaric, Nora Nikolac Gabaj, Sasa Kralik-Oguic, Ana Katusic Bojanac, Davor Jezek, Nino Sincic
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.686149/full