Hybrid inorganic-organic capsules for efficient intracellular delivery of novel siRNAs against influenza A (H1N1) virus infection

Abstract The implementation of RNAi technology into the clinical practice has been significantly postponing due to the issues regarding to the delivery of naked siRNA predominantly to target cells. Here we report the approach to enhance the efficiency of siRNA delivery by encapsulating the siRNA int...

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Bibliographic Details
Main Authors: Alexander S. Timin, Albert R. Muslimov, Aleksandra V. Petrova, Kirill V. Lepik, Maria V. Okilova, Andrey V. Vasin, Boris V. Afanasyev, Gleb B. Sukhorukov
Format: Article
Language:English
Published: Nature Publishing Group 2017-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-00200-0