Enhanced interleukin-8 production in mononuclear cells in severe pediatric obstructive sleep apnea

Abstract Background Obstructive sleep apnea (OSA) is a risk factor for cardiovascular disease, metabolic disorders, and cognitive dysfunction. Current thinking links chronic intermittent hypoxia (CIH) with oxidative stress and systemic inflammation. However, the sequence of events leading to the mor...

Full description

Bibliographic Details
Main Authors: Danbing Ke, Yuji Kitamura, Duncan Lejtenyi, Bruce Mazer, Robert T. Brouillette, Karen Brown
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Allergy, Asthma & Clinical Immunology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13223-019-0338-1