Establishment of Prostate Tumor Growth and Metastasis Is Supported by Bone Marrow Cells and Is Mediated by PIP5K1α Lipid Kinase

Establishment of Prostate Tumor Growth and Metastasis Is Supported by Bone Marrow Cells and Is Mediated by PIP5K1α Lipid Kinase

Cancer cells facilitate growth and metastasis by using multiple signals from the cancer-associated microenvironment. However, it remains poorly understood whether prostate cancer (PCa) cells may recruit and utilize bone marrow cells for their growth and survival. Furthermore, the regulatory mechanis...

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Bibliographic Details
Main Authors: Richard Karlsson, Per Larsson, Regina Miftakhova, Azharuddin Sajid Syed Khaja, Martuza Sarwar, Julius Semenas, Sa Chen, Andreas Hedblom, Tianyan Wang, Kristina Ekström-Holka, Athanasios Simoulis, Anjani Kumar, Niels Ødum, Thomas Grundström, Jenny L. Persson
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cancers
Subjects:
prostate cancer metastasis
bone marrow cells
PIP5K1α
therapeutic interventions
Online Access:https://www.mdpi.com/2072-6694/12/9/2719

Internet

https://www.mdpi.com/2072-6694/12/9/2719

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