Quantitative informant‐ and self‐reports of subjective cognitive decline predict amyloid beta PET outcomes in cognitively unimpaired individuals independently of age and APOE ε4

Quantitative informant‐ and self‐reports of subjective cognitive decline predict amyloid beta PET outcomes in cognitively unimpaired individuals independently of age and APOE ε4

Abstract Introduction Amyloid beta (Aβ) pathology is an Alzheimer's disease early hallmark. Here we assess the value of longitudinal self‐ and informant reports of cognitive decline to predict Aβ positron emission tomography (PET) outcome in cognitively unimpaired middle‐aged individuals. Metho...

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Bibliographic Details
Main Authors: Gonzalo Sánchez‐Benavides, Gemma Salvadó, Eider M. Arenaza‐Urquijo, Oriol Grau‐Rivera, Marc Suárez‐Calvet, Marta Milà‐Alomà, José María González‐de‐Echávarri, Carolina Minguillon, Marta Crous‐Bou, Aida Niñerola‐Baizán, Andrés Perissinotti, Juan Domingo Gispert, José Luis Molinuevo, for the ALFA Study
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Subjects:
Alzheimer's disease
amyloid
informant reports
preclinical
subjective cognitive decline
Online Access:https://doi.org/10.1002/dad2.12127

Internet

https://doi.org/10.1002/dad2.12127

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