Cannabinoid receptor CB2 ablation protects against TAU induced neurodegeneration

Cannabinoid receptor CB2 ablation protects against TAU induced neurodegeneration

Abstract Tauopathies are a group of neurodegenerative diseases characterized by the alteration/aggregation of TAU protein, for which there is still no effective treatment. Therefore, new pharmacological targets are being sought, such as elements of the endocannabinoid system (ECS). We analysed the o...

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Bibliographic Details
Main Authors: M. Galán-Ganga, C. Rodríguez-Cueto, J. Merchán-Rubira, F. Hernández, J. Ávila, M. Posada-Ayala, J. L. Lanciego, E. Luengo, M. G. Lopez, A. Rábano, J. Fernández-Ruiz, I. Lastres-Becker
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Acta Neuropathologica Communications
Subjects:
TAU
Cannabinoid receptor
CB2
Alzheimer’s disease
Neurodegeneration
Neuroinflammation
Online Access:https://doi.org/10.1186/s40478-021-01196-5

Internet

https://doi.org/10.1186/s40478-021-01196-5

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