The role of SCF ubiquitin-ligase complex at the beginning of life

Abstract As the largest family of E3 ligases, the Skp1-cullin 1-F-box (SCF) E3 ligase complex is comprised of Cullins, Skp1 and F-box proteins. And the SCF E3 ubiquitin ligases play an important role in regulating critical cellular processes, which promote degradation of many cellular proteins, incl...

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Bibliographic Details
Main Authors: Jiayan Xie, Yimei Jin, Guang Wang
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Reproductive Biology and Endocrinology
Subjects:
SCF
OET
Online Access:https://doi.org/10.1186/s12958-019-0547-y