The flavonoid 7,8-DHF fosters prenatal brain proliferation potency in a mouse model of Down syndrome

Abstract Neurogenesis impairment is a key determinant of intellectual disability in Down syndrome (DS), a genetic pathology due to triplication of chromosome 21. Since neurogenesis ceases after birth, apart in the hippocampus and olfactory bulb, the only means to tackle the problem of neurogenesis i...

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Bibliographic Details
Main Authors: Fiorenza Stagni, Beatrice Uguagliati, Marco Emili, Andrea Giacomini, Renata Bartesaghi, Sandra Guidi
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-85284-5