Synthesis of 2-Cyanopyrimidines

Synthesis of 2-Cyanopyrimidines

4,6-Dichloro-2-(methylthio)pyrimidine (<b>7</b>) was converted to 4-chloro-6-methoxy-2-(methylthio)pyrimidine (<b>15</b>) and 4,6-dimethoxy-2-(methylthio)pyrimidine (<b>14</b>). Chlorination of the latter with <i>N</i>-chlorosuccinimide (NCS) affords 5...

Full description

Bibliographic Details
Main Authors: Andreas S. Kalogirou, Panayiotis A. Koutentis
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Molbank
Subjects:
heterocycle
pyrimidine
nucleophilic displacement
chlorination
Online Access:https://www.mdpi.com/1422-8599/2019/4/M1086

Internet

https://www.mdpi.com/1422-8599/2019/4/M1086

Similar Items