Synthesis of 2-Cyanopyrimidines

Synthesis of 2-Cyanopyrimidines

4,6-Dichloro-2-(methylthio)pyrimidine (<b>7</b>) was converted to 4-chloro-6-methoxy-2-(methylthio)pyrimidine (<b>15</b>) and 4,6-dimethoxy-2-(methylthio)pyrimidine (<b>14</b>). Chlorination of the latter with <i>N</i>-chlorosuccinimide (NCS) affords 5...

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Bibliographic Details
Main Authors:	Andreas S. Kalogirou, Panayiotis A. Koutentis
Format:	Article
Language:	English
Published:	MDPI AG 2019-10-01
Series:	Molbank
Subjects:	heterocycle pyrimidine nucleophilic displacement chlorination
Online Access:	https://www.mdpi.com/1422-8599/2019/4/M1086

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