An improved Bayesian network method for reconstructing gene regulatory network based on candidate auto selection

An improved Bayesian network method for reconstructing gene regulatory network based on candidate auto selection

Abstract Background The reconstruction of gene regulatory network (GRN) from gene expression data can discover regulatory relationships among genes and gain deep insights into the complicated regulation mechanism of life. However, it is still a great challenge in systems biology and bioinformatics....

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Bibliographic Details
Main Authors: Linlin Xing, Maozu Guo, Xiaoyan Liu, Chunyu Wang, Lei Wang, Yin Zhang
Format: Article
Language:English
Published: BMC 2017-11-01
Series:BMC Genomics
Subjects:
Gene regulatory networks
Bayesian network
Candidate auto selection
Breakpoint detection
Search space reduction
Online Access:http://link.springer.com/article/10.1186/s12864-017-4228-y

Internet

http://link.springer.com/article/10.1186/s12864-017-4228-y

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