Sub-Lethal 5-Fluorouracil Dose Challenges Planarian Stem Cells Promoting Transcriptional Profile Changes in the Pluripotent Sigma-Class Neoblasts

Under physiological conditions, the complex planarian neoblast system is a composite of hierarchically organized stem cell sub-populations with sigma-class neoblasts, including clonogenic neoblasts, endowed with larger self-renewal and differentiation capabilities, thus generating all the other sub-...

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Bibliographic Details
Main Authors: Gaetana Gambino, Chiara Ippolito, Monica Evangelista, Alessandra Salvetti, Leonardo Rossi
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/11/7/949