Chronic treatment with hydroalcoholic extract of Plathymenia reticulata promotes islet hyperplasia and improves glycemic control in diabetic rats

Chronic treatment with hydroalcoholic extract of Plathymenia reticulata promotes islet hyperplasia and improves glycemic control in diabetic rats

ABSTRACT Objective: To investigate the anti-hyperglycemic effects of Plathymenia reticulata hydroalcoholic extract and related changes in body weight, lipid profile and the pancreas. Methods: Diabetes was induced in 75 adult male Wistar rats via oral gavage of 65mg/Kg of streptozotocin. Rats were...

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Bibliographic Details
Main Authors: Fernanda Oliveira Magalhães, Elizabeth Uber-Bucek, Patricia Ibler Bernardo Ceron, Thiago Fellipe Name, Humberto Eustáquio Coelho, Claudio Henrique Gonçalves Barbosa, Tatiane Carvalho, Milton Groppo
Format: Article
Language:English
Published: Instituto Israelita de Ensino e Pesquisa Albert Einstein
Series:Einstein (São Paulo)
Subjects:
Plathymenia reticulada
Diabetes mellitus
Streptozocin
Islets of langerhans
Plant extracts
Fabaceae
Pancreas
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082019000300213&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082019000300213&lng=en&tlng=en

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