Persistent Increases of PKMζ in Sensorimotor Cortex Maintain Procedural Long-Term Memory Storage

Summary: Procedural motor learning and memory are accompanied by changes in synaptic plasticity, neural dynamics, and synaptogenesis. Missing is information on the spatiotemporal dynamics of the molecular machinery maintaining these changes. Here we examine whether persistent increases in PKMζ, an a...

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Bibliographic Details
Main Authors: Peng Penny Gao, Jeffrey H. Goodman, Todd Charlton Sacktor, Joseph Thachil Francis
Format: Article
Language:English
Published: Elsevier 2018-07-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004218300907