Tumor Immune Microenvironment Clusters in Localized Prostate Adenocarcinoma: Prognostic Impact of Macrophage Enriched/Plasma Cell Non-Enriched Subtypes

Tumor Immune Microenvironment Clusters in Localized Prostate Adenocarcinoma: Prognostic Impact of Macrophage Enriched/Plasma Cell Non-Enriched Subtypes

Background: Prostate cancer (PCa) is characterized by significant heterogeneity in its molecular, genomic, and immunologic characteristics. Methods: Whole transcriptome RNAseq data from The Cancer Genome Atlas of prostate adenocarcinomas (<i>n</i> = 492) was utilized. The immune microenv...

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Bibliographic Details
Main Authors: Neil K. Jairath, Mark W. Farha, Sudharsan Srinivasan, Ruple Jairath, Michael D. Green, Robert T. Dess, William C. Jackson, Adam B. Weiner, Edward M. Schaeffer, Shuang G. Zhao, Felix Y. Feng, Issam El Naqa, Daniel E. Spratt
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Journal of Clinical Medicine
Subjects:
prostate cancer
immunotherapy
radiation therapy
macrophages
RNAseq
tumor immune microenvironment
Online Access:https://www.mdpi.com/2077-0383/9/6/1973

Internet

https://www.mdpi.com/2077-0383/9/6/1973

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