Tacrolimus Protects Podocytes from Injury in Lupus Nephritis Partly by Stabilizing the Cytoskeleton and Inhibiting Podocyte Apoptosis.

Tacrolimus Protects Podocytes from Injury in Lupus Nephritis Partly by Stabilizing the Cytoskeleton and Inhibiting Podocyte Apoptosis.

Several studies have reported that tacrolimus (TAC) significantly reduced proteinuria in lupus nephritis (LN) patients and mouse models. However, the mechanism for this effect remains undetermined. This study explored the mechanism of how TAC protects podocytes from injury to identify new targets fo...

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Bibliographic Details
Main Authors: Ruyi Liao, Qinghua Liu, Zhihua Zheng, Jinjin Fan, Wenxing Peng, Qingyu Kong, Huijuan He, Shicong Yang, Wenfang Chen, Xueqing Tang, Xueqing Yu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4498640?pdf=render

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http://europepmc.org/articles/PMC4498640?pdf=render

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