TGF-b downregulation by RNAi technique in ex vivo-expanded HSCs on 3D DBM scaffold
Background: Bone Marrow Transplantations (BMT) are limited by low CD34+ cell counts in umbilical cord blood (UCB) and these cells need to be expanded for success in such procedures. To achieve this goal, ex vivo expansion of hematopoietic stem cells (HSCs) by enhancing their self-renewal activity on...
Main Authors: | , , , , |
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Format: | Article |
Language: | fas |
Published: |
Tehran University of Medical Sciences
2012-05-01
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Series: | Tehran University Medical Journal |
Subjects: | |
Online Access: | http://tumj.tums.ac.ir/browse.php?a_code=A-10-25-142&slc_lang=en&sid=1 |