Receptor-based mechanism of relative sensing and cell memory in mammalian signaling networks

Receptor-based mechanism of relative sensing and cell memory in mammalian signaling networks

Detecting relative rather than absolute changes in extracellular signals enables cells to make decisions in constantly fluctuating environments. It is currently not well understood how mammalian signaling networks store the memories of past stimuli and subsequently use them to compute relative signa...

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Bibliographic Details
Main Authors: Eugenia Lyashenko, Mario Niepel, Purushottam D Dixit, Sang Kyun Lim, Peter K Sorger, Dennis Vitkup
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-01-01
Series:eLife
Subjects:
relative sensing
receptor endocytosis
EGFR
cell memory
signaling networks
Online Access:https://elifesciences.org/articles/50342

Internet

https://elifesciences.org/articles/50342

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