Maintenance of HDACs and H3K9me3 Prevents Arterial Flow-Induced Venous Endothelial Damage

Maintenance of HDACs and H3K9me3 Prevents Arterial Flow-Induced Venous Endothelial Damage

The transition of flow microenvironments from veins to arteries in vein graft surgery induces “peel-off” of venous endothelial cells (vECs) and results in restenosis. Recently, arterial laminar shear stress (ALS) and oscillatory shear stress (OS) have been shown to affect the cell cycle and inflamma...

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Bibliographic Details
Main Authors: Ting-Yun Wang, Ming-Min Chang, Yi-Shuan Julie Li, Tzu-Chieh Huang, Shu Chien, Chia-Ching Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
shear stress
venous endothelial cell
HDACs
H3K9me3
FAK
ITSA-1
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.642150/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.642150/full

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