Mutations in ARX result in several defects involving GABAergic neurons

Genetic investigations of X-linked mental retardation have demonstrated the implication of ARX in a wide spectrum of disorders extending from phenotypes with severe neuronal migration defects, such as lissencephaly, to mild or moderate forms of mental retardation without apparent brain abnormalities...

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Bibliographic Details
Main Authors: Gaelle Friocourt, John G Parnavelas
Format: Article
Language:English
Published: Frontiers Media S.A. 2010-03-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2010.00004/full