The role of macrophage migration inhibitory factor in mast cell-stimulated fibroblast proliferation and collagen production.

Current clinical and translational studies have shown that mast cell plays a pivotal role in multiple fibrotic diseases including scleroderma. However, the lack of mature human mast cell culture model exhibits a major obstacle for further dissection of cytokines and signaling molecules required for...

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Bibliographic Details
Main Authors: Gu Ningyan, Yao Xu, Shi Hongfei, Chen Jingjing, Chen Min
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4380314?pdf=render