Activation of IRF1 in Human Adipocytes Leads to Phenotypes Associated with Metabolic Disease

The striking rise of obesity-related metabolic disorders has focused attention on adipocytes as critical mediators of disease phenotypes. To better understand the role played by excess adipose in metabolic dysfunction it is crucial to decipher the transcriptional underpinnings of the low-grade adipo...

Full description

Bibliographic Details
Main Authors: Max Friesen, Raymond Camahort, Youn-Kyoung Lee, Fang Xia, Robert E. Gerszten, Eugene P. Rhee, Rahul C. Deo, Chad A. Cowan
Format: Article
Language:English
Published: Elsevier 2017-05-01
Series:Stem Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671117301200