Zika Virus NS2A-Mediated Virion Assembly

ZIKV is a recently emerged mosquito-borne flavivirus that can cause devastating congenital Zika syndrome in pregnant women and Guillain-Barré syndrome in adults. The molecular mechanism of ZIKV virion assembly is largely unknown. Here, we report that ZIKV NS2A plays a central role in recruiting vira...

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Bibliographic Details
Main Authors: Xianwen Zhang, Xuping Xie, Hongjie Xia, Jing Zou, Linfen Huang, Vsevolod L. Popov, Xinwen Chen, Pei-Yong Shi
Format: Article
Language:English
Published: American Society for Microbiology 2019-10-01
Series:mBio
Subjects:
Online Access:https://doi.org/10.1128/mBio.02375-19