Cumulative inactivated vaccine exposure and allergy development among children: a birth cohort from Japan

Abstract Background Adjuvants used in inactivated vaccines often upregulate type 2 immunity, which is dominant in allergic diseases. We hypothesised that cumulative adjuvant exposure in infancy may influence the development of allergies later in life by changing the balance of type 1/type 2 immunity...

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Bibliographic Details
Main Authors: Kiwako Yamamoto-Hanada, Kyongsun Pak, Mayako Saito-Abe, Limin Yang, Miori Sato, Hidetoshi Mezawa, Hatoko Sasaki, Minaho Nishizato, Mizuho Konishi, Kazue Ishitsuka, Kenji Matsumoto, Hirohisa Saito, Yukihiro Ohya, Japan Environment and Children’s Study (JECS) Group
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Environmental Health and Preventive Medicine
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12199-020-00864-7