Expression of <it>BLIMP1/PRMT5 </it>and concurrent histone H2A/H4 arginine 3 dimethylation in fetal germ cells, CIS/IGCNU and germ cell tumors

<p>Abstract</p> <p>Background</p> <p>Most testicular germ cell tumors arise from intratubular germ cell neoplasia unclassified (IGCNU, also referred to as carcinoma <it>in situ</it>), which is thought to originate from a transformed primordial germ cell (PGC...

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Bibliographic Details
Main Authors: Müller Annette M, Jäck Hans-Martin, Steger Klaus, Gillis Ad JM, Nettersheim Daniel, Biermann Katharina, Eckert Dawid, Looijenga Leendert HJ, Schorle Hubert
Format: Article
Language:English
Published: BMC 2008-11-01
Series:BMC Developmental Biology
Online Access:http://www.biomedcentral.com/1471-213X/8/106