Quinazoline Derivatives Designed as Efflux Pump Inhibitors: Molecular Modeling and Spectroscopic Studies

Multidrug resistance of bacteria is a worrying concern in the therapeutic field and an alternative method to combat it is designing new efflux pump inhibitors (EPIs). This article presents a molecular study of two quinazoline derivatives, labelled BG1189 and BG1190, proposed as EPIs. <i>In sil...

Full description

Bibliographic Details
Main Authors: Ana-Maria Udrea, Andra Dinache, Jean-Marie Pagès, Ruxandra Angela Pirvulescu
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Molecules
Subjects:
MDR
Online Access:https://www.mdpi.com/1420-3049/26/8/2374