Increased DNA Copy Number Variation Mosaicism in Elderly Human Brain

Aging is a complex process strongly determined by genetics. Previous reports have shown that the genome of neuronal cells displays somatic genomic mosaicism including DNA copy number variations (CNVs). CNVs represent a significant source of genetic variation in the human genome and have been implica...

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Bibliographic Details
Main Authors: Darine Villela, Claudia K. Suemoto, Renata Leite, Carlos Augusto Pasqualucci, Lea T. Grinberg, Peter Pearson, Carla Rosenberg
Format: Article
Published: Hindawi Limited 2018-01-01
Series:Neural Plasticity
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