Increased DNA Copy Number Variation Mosaicism in Elderly Human Brain

Increased DNA Copy Number Variation Mosaicism in Elderly Human Brain

Aging is a complex process strongly determined by genetics. Previous reports have shown that the genome of neuronal cells displays somatic genomic mosaicism including DNA copy number variations (CNVs). CNVs represent a significant source of genetic variation in the human genome and have been implica...

Full description

Bibliographic Details
Main Authors:	Darine Villela, Claudia K. Suemoto, Renata Leite, Carlos Augusto Pasqualucci, Lea T. Grinberg, Peter Pearson, Carla Rosenberg
Format:	Article
Language:	English
Published:	Hindawi Limited 2018-01-01
Series:	Neural Plasticity
Online Access:	http://dx.doi.org/10.1155/2018/2406170

Similar Items

Germline DNA copy number variation in individuals with Argyrophilic grain disease reveals CTNS as a plausible candidate gene
by: Darine Villela, et al.
Published: (2013-01-01)

Differential DNA Methylation of MicroRNA Genes in Temporal Cortex from Alzheimer’s Disease Individuals
by: Darine Villela, et al.
Published: (2016-01-01)

MONTAGE: a new tool for high-throughput detection of mosaic copy number variation
by: Joseph T. Glessner, et al.
Published: (2021-02-01)

Perspective: DNA Copy Number Variations in Cardiovascular Diseases
by: Aatira Vijay, et al.
Published: (2018-12-01)

DNA Copy Number Variations as Markers of Mutagenic Impact
by: Galina Hovhannisyan, et al.
Published: (2019-09-01)

Variation of DNA copies number in etiology of congenital heart defects
by: A. A. Slepukhina, et al.
Published: (2018-11-01)

Mitochondrial DNA copy number variation across human cancers
by: Ed Reznik, et al.
Published: (2016-02-01)

Ribosomal DNA copy number loss and sequence variation in cancer.
by: Baoshan Xu, et al.
Published: (2017-06-01)

Genomic Copy Number Variation Affecting Genes Involved in the Cell Cycle Pathway: Implications for Somatic Mosaicism
by: Ivan Y. Iourov, et al.
Published: (2015-01-01)

Copy number variation and schizophrenia
by: Tam, Gloria Wing Chi
Published: (2009)

Simple binary segmentation frameworks for identifying variation in DNA copy number
by: Yang Tae Young
Published: (2012-10-01)

MSX2 copy number increase and craniosynostosis: copy number variation detected by array comparative genomic hybridization
by: Karla de Oliveira Pelegrino, et al.
Published: (2012-08-01)

Genomic copy number variation in schizophrenia
by: Rudd, Danielle Song
Published: (2014)

Copy number variation in African Americans
by: Caillier Stacy J, et al.
Published: (2009-03-01)

Copy number variation in Thai population.
by: Bhoom Suktitipat, et al.
Published: (2014-01-01)

New copy number variations in schizophrenia.
by: Chiara Magri, et al.
Published: (2010-01-01)

Copy number variation in the bovine genome
by: Bendixen Christian, et al.
Published: (2010-05-01)

Copy number variation in the horse genome.
by: Sharmila Ghosh, et al.
Published: (2014-10-01)

Copy number variation in bipolar disorder
by: Grozeva, Detelina
Published: (2010)

DNA copy number variations in children with vesicoureteral reflux and urinary tract infections.
by: Dong Liang, et al.
Published: (2019-01-01)

Copy number variation of ribosomal DNA and <it>Pokey </it>transposons in natural populations of <it>Daphnia</it>
by: Eagle Shannon HC, et al.
Published: (2012-03-01)

Age-Related and Heteroplasmy-Related Variation in Human mtDNA Copy Number.
by: Manja Wachsmuth, et al.
Published: (2016-03-01)

Bayesian DNA copy number analysis
by: Hutter Marcus, et al.
Published: (2009-01-01)

Copy number of the transposon, Pokey, in rDNA is positively correlated with rDNA copy number in Daphnia obtuse [corrected].
by: Kaitlynn LeRiche, et al.
Published: (2014-01-01)

Correction: Copy Number of the Transposon, Pokey, in rDNA Is Positively Correlated with rDNA Copy Number in Daphnia obtusa.
by: PLOS ONE Staff
Published: (2015-01-01)

A high-resolution map of segmental DNA copy number variation in the mouse genome.
by: Timothy A Graubert, et al.
Published: (2007-01-01)

Gene-resolution analysis of DNA copy number variation using oligonucleotide expression microarrays
by: Wenger Gail D, et al.
Published: (2007-04-01)

Copy Number Variation: Methods and Clinical Applications
by: Ondrej Pös, et al.
Published: (2021-01-01)

Copy number variation in familial Parkinson disease.
by: Nathan Pankratz, et al.
Published: (2011-01-01)

Copy Number Variation at the APOL1 Locus.
by: Rupam Ruchi, et al.
Published: (2015-01-01)

Evolutionary impact of copy number variation rates
by: Guillermo Rodrigo
Published: (2017-08-01)

Copy number variation across European populations.
by: Wanting Chen, et al.
Published: (2011-01-01)

Genomic characteristics of cattle copy number variations
by: Matukumalli Lakshmi K, et al.
Published: (2011-02-01)

Elusive copy number variation in the mouse genome.
by: Avigail Agam, et al.
Published: (2010-09-01)

Genetic Association Testing of Copy Number Variation
by: Li, Yinglei
Published: (2014)

Copy number variations in female infertility in China
by: Huang W, et al.
Published: (2019-08-01)

Analysis of Copy Number Variation in Esophageal Cancer
by: Zachariah James Pollock, et al.
Published: (2015)

Genetic association studies of copy-number variation: should assignment of copy number states precede testing?
by: Patrick Breheny, et al.
Published: (2012-01-01)

The Role of Number of Copies, Structure, Behavior and Copy Number Variations (CNV) of the Y Chromosome in Male Infertility
by: Fabrizio Signore, et al.
Published: (2019-12-01)

Investigation of Copy Number Variation in Children with Conotruncal Heart Defects
by: Carla Marques Rondon Campos, et al.
Published: (2015-01-01)

Cannot write session to /tmp/vufind_sessions/sess_b9o84s91nt8qjguua48scnjfd3