Connectivity, Pharmacology and Computation: Towards a Mechanistic Understanding of Neural System Dysfunction in Schizophrenia

Connectivity, Pharmacology and Computation: Towards a Mechanistic Understanding of Neural System Dysfunction in Schizophrenia

Neuropsychiatric diseases such as schizophrenia and bipolar illness alter the structure and function of distributed neural networks. Functional neuroimaging tools have evolved sufficiently to reliably detect system-level disturbances in neural networks. This review focuses on recent findings in schi...

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Bibliographic Details
Main Authors: Alan eAnticevic, Michael W Cole, Grega eRepovš, Aleksandar eSavic, Naomi R Driesen, Genevieve eYang, Youngsun T Cho, John David Murray, David C Glahn, Xiao-Jing eWang, John H Krystal
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Psychiatry
Subjects:
Pharmacology
Schizophrenia
Thalamus
computational modeling
Glutamate
functional connectivity
Online Access:http://journal.frontiersin.org/Journal/10.3389/fpsyt.2013.00169/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fpsyt.2013.00169/full

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