A Pilot Cross-Sectional Study to Investigate the Biomarker Potential of Phosphorylated Neurofilament-H and Immune Mediators of Disability in Patients With 5 Year Relapsing-Remitting Multiple Sclerosis

A Pilot Cross-Sectional Study to Investigate the Biomarker Potential of Phosphorylated Neurofilament-H and Immune Mediators of Disability in Patients With 5 Year Relapsing-Remitting Multiple Sclerosis

Objective: To test the feasibility of conducting a full-scale project evaluating the potential value of the phosphorylated neurofilament H (pNF-H) and several cytokines as disability markers in relapsing-remitting multiple sclerosis (RRMS).Methods: Twenty-four patients with 5-year RRMS evolution and...

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Bibliographic Details
Main Authors: María Inés Herrera, Rodolfo Alberto Kölliker-Frers, Matilde Otero-Losada, Santiago Perez Lloret, Macarena Filippo, Julia Tau, Francisco Capani, Andrés M. Villa
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Neurology
Subjects:
relapsing-remitting multiple sclerosis
biomarker potential
neurofilament heavy chain phosphoform
cytokines
disability progression
expanded disability status scale
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.01046/full

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https://www.frontiersin.org/article/10.3389/fneur.2019.01046/full

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