Transcriptional autoregulatory loops are highly conserved in vertebrate evolution.

BACKGROUND: Feedback loops are the simplest building blocks of transcriptional regulatory networks and therefore their behavior in the course of evolution is of prime interest. METHODOLOGY: We address the question of enrichment of the number of autoregulatory feedback loops in higher organisms. Firs...

Full description

Bibliographic Details
Main Authors: Szymon M Kiełbasa, Martin Vingron
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2527657?pdf=render