Degeneration of Lumbar Intervertebral Discs: Characterization of Anulus Fibrosus Tissue and Cells of Different Degeneration Grades

Degeneration of Lumbar Intervertebral Discs: Characterization of Anulus Fibrosus Tissue and Cells of Different Degeneration Grades

Intervertebral disc (IVD) herniation and degeneration is a major source of back pain. In order to regenerate a herniated and degenerated disc, closure of the anulus fibrosus (AF) is of crucial importance. For molecular characterization of AF, genome-wide Affymetrix HG-U133plus2.0 microarrays of nati...

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Bibliographic Details
Main Authors: Stefan Stich, Michal Jagielski, Anja Fleischmann, Carola Meier, Patricia Bussmann, Benjamin Kohl, Julia Schmidt, Jan-Philipp Krüger, Michaela Endres, Mario Cabraja, Kolja Reimann, Dominik Laue, Wolfgang Ertel, Michael Sittinger
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:International Journal of Molecular Sciences
Subjects:
intervertebral disc
anulus fibrosus
degeneration
genome-wide microarray
Online Access:https://www.mdpi.com/1422-0067/21/6/2165

Internet

https://www.mdpi.com/1422-0067/21/6/2165

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