Drug Resistance Mutations Against Protease, Reverse Transcriptase and Integrase Inhibitors in People Living With HIV-1 Receiving Boosted Protease Inhibitors in South Africa

Drug Resistance Mutations Against Protease, Reverse Transcriptase and Integrase Inhibitors in People Living With HIV-1 Receiving Boosted Protease Inhibitors in South Africa

The South African national combination antiretroviral therapy (cART) roll-out program started in 2006, with over 4.4 million people accessing treatment since it was first introduced. HIV-1 drug resistance can hamper the success of cART. This study determined the patterns of HIV-1 drug-resistance ass...

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Bibliographic Details
Main Authors: Adetayo Emmanuel Obasa, Sello Given Mikasi, Dominik Brado, Ruben Cloete, Kamlendra Singh, Ujjwal Neogi, Graeme Brendon Jacobs
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Microbiology
Subjects:
HIV-1
reverse transcriptase inhibitor (RTI)
protease inhibitor (PI)
integrase strand-transfer inhibitor (InSTI)
resistance
South Africa
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.00438/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2020.00438/full

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