Pseudomonas aeruginosa Biofilm Formation and Persistence, along with the Production of Quorum Sensing-Dependent Virulence Factors, Are Disrupted by a Triterpenoid Coumarate Ester Isolated from Dalbergia trichocarpa, a Tropical Legume.

Pseudomonas aeruginosa Biofilm Formation and Persistence, along with the Production of Quorum Sensing-Dependent Virulence Factors, Are Disrupted by a Triterpenoid Coumarate Ester Isolated from Dalbergia trichocarpa, a Tropical Legume.

Recently, extracts of Dalbergia trichocarpa bark have been shown to disrupt P. aeruginosa PAO1 quorum sensing (QS) mechanisms, which are key regulators of virulence factor expression and implicated in biofilm formation. One of the active compounds has been isolated and identified as oleanolic aldehy...

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Main Authors: Tsiry Rasamiravaka, Olivier M Vandeputte, Laurent Pottier, Joelle Huet, Christian Rabemanantsoa, Martin Kiendrebeogo, Abel Andriantsimahavandy, Andry Rasamindrakotroka, Caroline Stévigny, Pierre Duez, Mondher El Jaziri
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4505864?pdf=render

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http://europepmc.org/articles/PMC4505864?pdf=render

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